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Coinfection in SARS-CoV-2 infected patients: Where are influenza virus and rhinovirus/enterovirus?

Michael D. Nowak Emilia M. Sordillo Melissa R. Gitman Alberto E. Paniz Mondolfi
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Infection with the new pandemic pathogen severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) can cause a wide range of disease varying from mild cold‐like symptoms to complicated pneumonia, severe inflammatory response, and death. Although available data have been limited, recent case reports of concurrent infections with influenza virus, human metapneumovirus, and seasonal coronaviruses such as CoV‐HKU‐1 in adults and children with SARS‐CoV‐2 infection have suggested that coinfection may influence morbidity and mortality. A recent study by Kim et al found that coinfections were frequent in their patient population in Northern California; more than 20% of 116 SARS‐CoV‐2 positive specimens also contained one or more additional respiratory pathogens, most often rhinovirus/enterovirus, respiratory syncytial virus, and non‐SARS Coronaviridae. Conversely, 7.5% of their specimens positive for a non‐SARS‐CoV‐2 respiratory pathogen were also positive for SARS‐CoV‐2. In addition, a study from Wuhan examining 8274 patients with 2745 confirmed SARS‐CoV‐2 cases revealed that 5.8% of SARS‐CoV‐2 infected and 18.4% of non‐SARS‐CoV‐2‐infected patients had coinfections.

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Publicado en el sitio 2020-12-13 11:59:38

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