The Cuban Ministry of Public Health’s Protocol for Attention to COVID-19 Patients establishes that case confirmations are determined by positive virological tests of persons with and without symptoms.[1] These studies are carried out for SARS-CoV-2 by real-time polymerase chain reaction (RT-PCR) in specimens of respiratory mucosa collected via nasopharyngeal swab. The Protocol also establishes three types of discharge: microbiological (based on negative RT-PCR), clinical-imaging (no signs or symptoms and negative chest scan) and epidemiological (14 days after negative RT-PCR). A microbiological release from hospital is warranted when a patient tests negative by RT-PCR at nine days after testing positive.