Nursing home residents have high morbidity and mortality due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Spread of the virus within nursing homes has been estimated in point prevalence surveys using real time reverse transcriptase polymerase-chain reaction (RT-PCR) and naso/oro-pharyngeal swabs. These surveys have revealed high rates of SARS-CoV-2 infection in residents, which is frequently asymptomatic or presents with atypical symptoms.However, the true incidence of infection and the extent of possible future protection from re-infection in this group is unclear.